产品货号：
Z35272
中文名称：
P53/TP53抗体
英文名称：
Anti-P53/TP53 Antibody (Clone#BP53-12)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-P53/TP53 Antibody (Clone#BP53-12) |
| 指标别名 | Antigen NY CO 13;Cellular tumor antigen p53;LFS1;P53;Phosphoprotein p53;TP53;TRP53;tumor protein p53;Tumor suppressor p53 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,ICC |
| 基因名称 | TP53 |
| 克隆号 | BP53-12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Recombinant human wild-type p53 protein. |
| 实际分子量 | 53KD |
| 成分 | 200μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Ascites |
| 浓度 | 200μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells.The protein is also detectable in many actively proliferating,nontransformed cells,but it is undetectable or present at low levels in resting cells.This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage,respectively,by differential transcription of target genes and through transcription-independent apoptotic functions.The p53 protein contains 393 amino acids.Human p53 tumour antigen is Locatedto band 17p13.p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis. |
| Uniprot ID | P04637 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | tumor protein p53 |
| 蛋白名全称 | Cellular tumor antigen p53 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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